24,804 Views By Órla Ryan Share Tweet Email Briana O’Doherty at Connolly station in 2014, after she took a train with other pro-choice campaigners from Dublin to Belfast to bring back abortion pills. Source: Brian Lawless PA Archive/PA ImagesROSA IRELAND IS planning to distribute abortion pills to cities and universities around Ireland.The organisation is part of the movement calling for the Eighth Amendment of the Constitution, which gives equal status to the unborn and the mother, to be repealed.The ‘Bus 4 Repeal’ will start its journey in Dublin on 6 March before travelling to a number of cities and universities, and returning to the capital on 8 March.In a statement, Rosa said the purpose of the tour is “both to provide direct assistance to those in need of safe abortion pills and to campaign for the repeal of the Eighth Amendment to legalise abortion in Ireland”. 171 Comments Source: RosaThe planned route is as follows:Monday 6 MarchUniversity College DublinWaterford ITCork CityTuesday 7 MarchUniversity College CorkLimerick CityGalway CityWednesday 8 MarchNUI GalwayNUI MaynoothDublin CityThe Citizens’ Assembly, made up of a chairperson and 99 citizens, has held a number of hearings about abortion and is expected to deliver a report in the coming months on whether or not a referendum on repealing the Eighth Amendment should take place.The assembly received over 13,000 submissions about the issue. Both pro- and anti-amendment groups had encouraged members of the public to submit their views for consideration.Read: Citizens’ Assembly given extra day to discuss abortion issueRead: Citizens’ Assembly receives over 13,000 submissions about abortionRead: Study shows vast majority of Irish women who took abortion pills feel they made right decision http://jrnl.ie/3216154 Wednesday 1 Feb 2017, 7:57 AM Feb 1st 2017, 7:57 AM Tweet thisShare on FacebookEmail this article Short URL ‘Repeal’ bus to distribute abortion pills in cities and colleges around Ireland Rosa said the tour will “provide direct assistance to those in need of safe abortion pills”.
Stay on target ‘Star Wars Pinball’ Has Your Favorite Brand in Ball FormSNES Games Officially Come to Nintendo Switch If you have a Nintendo Switch, chances are you also have The Legend of Zelda: Breath of the Wild. The new Zelda is a massive, phenomenal game that you can and should play for dozens of hours. But eventually, you’re going to want to play something new on your Nintendo console/handheld hybrid. Switch Games That Aren’t Zelda is a new column highlighting cool, smaller Switch games to check out once you’ve saved Hyrule.I thought my confessional on why I don’t like roguelikes might be the last thing I’d ever have to write about the genre. However, a significant amount of the intriguing indie games coming to Nintendo Switch That Aren’t Zelda draw inspiration from this accursed unforgiving strain of permadeath RPGs. Beloved blasphemy blaster The Binding of Isaac is already available and soon we’ll get to play Enter the Gungeon and Tumbleseed and Gonner and who knows what else. So if I’m going to keep writing these columns, roguelikes are still in my future, roguelikes such as Has-Been Heroes (also available on other platforms).Published by GameStop’s new indie label GameTrust, Has-Been Heroes has a slight but serviceable set-up. Players control three warriors, two of whom used to be glorious heroes before they got old, escorting twin princesses across monster-infested lands. Once you inevitably die, a friendly deity collects the souls of monsters you have slain and gives you rewards as well as a new chance at life. Roguelikes tend to find clever ways to justify their endless loops, and Has-Been Heroes opts for a comedic, Groundhog Day tone.The story may be shallow, but the mechanics are the exact opposite, and somewhat difficult to describe in words. Three face buttons correspond to the three heroes in three different lanes. As monsters walk down one lane and can attack them. With the right timing, you can swap heroes in and out of lanes for combo attacks.It’s a lot of coordination to wrap your head around, but elaborate attacks aren’t optional. Enemies get tough quick, often dealing one-hit kills once they reach you, and they usually need to be stunned before they can be damaged. So you’ll have to use tactics like breaking a monster’s guard with the Rogue’s multi-strike attack and then dealing damage with the Warrior’s massive sword swing or the Monk’s staff, all while making sure attacks will be recharged in time for the next closest enemies.Combat is technically real-time, but you can pause at will to plan your next moves and reduce tension somewhat. If you are in a pinch, you can also use spells that shoot fireballs or multiply your attacks. In-between battles make sure to visit shops that sell random new spells and items.These mechanics aren’t immediately intuitive, but after enough deaths and restarts, I did begin to respect their fascinating complexity. I enjoyed pulling off smart and efficient combos that made use of every party member’s unique strengths. It’s almost like fantasy RPG Plants vs. Zombies. I just wish this gameplay was in a game that wasn’t a roguelike.I promise not to repeat this every time I write about roguelikes but it’s hard for me to get invested in a game where progression constantly slips between your fingers. I would be very interested in a proper RPG with these mechanics alongside persistent stats and spells and items earned. But fighting the same early enemies and bosses with the same base abilities over and over again is just boring as well as frustratingly hard.I also wish Has-Been Heroes looked a bit better. The heroes themselves have nice cartoon designs and unlocking more of them is the game’s greatest reward, but the art style is a little flat and sparse. This is especially disappointing since developer Frozenbyte’s Trine games paired three-character, The Lost Vikings action with gorgeous visuals back on the Wii U.If you enjoy roguelikes and are looking for a Nintendo Switch Game That Isn’t Zelda, you can disregard much of what I just said and seriously consider giving Has-Been Heroes a shot. And even as a roguelike hater the unique mechanics were addictive enough to keep me coming back more often than I would’ve expected. But this wasn’t the game to change my mind about roguelikes. Until next time!Check back next week for another Switch Game That Isn’t Zelda.Want to learn more? Here’s everything you need to know about the Nintendo Switch.Buy it now!The Legend of Zelda: Breath of the WindNintendo SwitchEssential Nintendo Switch Accessories
Starting this month, Vancouver shoppers might notice a colorful new addition to the wine and beer lineup at the supermarket. The city is set to become a test market for a new wine spritzer line from MillerCoors, the American branch of multinational brewing company MolsonCoors.The new product line, called Movo, is part of an effort by the company to branch out and establish itself in other markets beyond beer.“You either innovate or you die,” said Sofia Colucci, vice president of innovations for MillerCoors. “We recognize that we have not done enough. We need to do more and we are going faster, taking risks and listening to our distributors because they know the business better than anyone.”The 100-calorie Movo spritzers are available in Raspberry Rose, Peach White Blend and Blood Orange Sangria flavors, and are sold in 8.4-ounce cans that are 5.5 percent alcohol by volume. MillerCoors prominently declares that the sparkling beverage is made with “real wine, natural ingredients and no sugar added.”According to MillerCoors spokesman Marty Maloney, Movo was scheduled to roll out in Vancouver around the end of April, and will be sold at approximately 150-200 locations including grocery stores, convenience stores, liquor stores and at bars and restaurants for on-premises consumption.
Lendlease has linked its physical office environment to its employees’ health and wellbeing.The property and infrastructure organisation has partnered with Delos to develop a building standard that actively contribute to employees’ health, wellbeing and performance, and it intends to lead by example by implementing the initiative among its own workforce.The employer is introducing the standard as part of its commitment to the health and wellbeing of its employees. As part of the initiative, Lendlease will evaluate its regional offices for health and wellness performance.Geoff Dutaillis, group head of sustainability at Lendlease, said: “The built environment has a critical role to play in helping cities and governments transition towards a low carbon future; however, it’s the direct impact on human capital and productivity through increased focus on supporting health and wellbeing which is the untapped potential.”
Beaver is a village in the Yukon Flats in the Interior .(Alaska DEC graphic)There’s been a large fuel spill in the Yukon Flats village of Beaver.A report from the Alaska Department of Environment Conservation says an estimated 3,000 gallons of diesel were released at the village school Tuesday. The DEC says a heavy equipment operator plowing snow damaged piping at a tank farm. It says a school maintenance worker closed a valve to halt the release. The fuel impacted area is about 600 feet from the Beaver Village well and the Yukon River.DEC says the Yukon Flat School district and Beaver Village Tribal Council are working with the agency on response to the spill, including a plan to excavate impacted soils
Julian Aguilar/The Texas TribuneOn the last day of the 85th legislative session, protesters opposed to Senate Bill 4 — the “sanctuary cities” law — fill up the rotunda of the state Capitol in Austin on May 29, 2017. After opponents of Texas’ immigration-enforcement law were delivered what they said was a “punch to the gut” by a federal appellate court, they stressed Wednesday that they weren’t completely out of the fight.A panel of three 5th U.S. Circuit Court of Appeals judges ruled Tuesday that most of Senate Bill 4 can remain in effect while the case plays out. That came after it was partially blocked by U.S. District Judge Orlando Garcia in San Antonio last summer.Attorneys and immigrants’ rights groups who fought against SB 4 said their next move isn’t clear but that they’re considering seeking a hearing before the entire 5th Circuit.“There are a lot of parties [involved], so we are coordinating on this,” Efrén Olivares, the racial and economic justice director for the Texas Civil Rights Project, told reporters during a conference call. “But procedurally, the next step would be to request an en banc hearing.” There is also the possibility of asking the U.S. Supreme Court, he said. Share The plaintiffs’ attorneys admitted Wednesday that they were not surprised at the ruling due to the 5th Circuit’s conservative leanings, so it’s unclear how much faith they will have in pleading their case before the entire court. But, they said, there remains the option to show that in its implementation, SB 4 leads to several constitutional violations.The legislation prohibits law enforcement supervisors from preventing their local law enforcement officers from questioning the immigration status of people they detain or arrest. It also punishes local government department heads and elected officials who don’t cooperate with federal immigration “detainers” — requests by agents to turn over immigrants subject to possible deportation — in the form of jail time and penalties that exceed $25,000, and it prohibits local entities from pursuing “a pattern or practice that ‘materially limits’ the enforcement of immigration laws” or prohibits “assisting or cooperating” with federal immigration officers as reasonable or necessary.Olivares said that while the next step in the appeals process is being considered, the lawyers and their supporters will also prepare for the case to head back to San Antonio. Tuesday’s ruling was only on the temporary injunction of SB 4; now, the district court is set to consider the law itself.In a statement released after Tuesday’s ruling, Texas Attorney General Ken Paxton said the decision shows the law doesn’t run afoul of the U.S. Constitution. “I’m pleased the 5th Circuit recognized that Senate Bill 4 is lawful, constitutional and protects the safety of law enforcement officers and all Texans,” he said. “Enforcing immigration law prevents the release of individuals from custody who have been charged with serious crimes.”One of the most controversial components of SB 4, what opponents call the “papers please” provision, was never halted and has been law since September. In his August ruling, Garcia allowed that part of the law to go into effect but said officers cannot prolong a stop for longer than necessary and can’t make an arrest solely based on immigration status. Olivares said he’s already heard this hasn’t always been the case and said that’s one of the challenges to the law that could be presented to the district judge.“Police officers are prolonging the stops on purpose just to allow for Border Patrol or [Immigration and Customs Enforcement] agents, and that is unconstitutional,” he said. “We know that is happening around the state and particularly in border areas, so we are keeping track of that.”Another option is for local governments to adopt or continue policies where being charged for an alleged misdemeanor doesn’t trigger automatic arrest, said Bob Libal, the executive director of Grassroots Leadership, an Austin-based immigrant rights and private-prison watchdog group.“Local officials need to act swiftly to stop the arrest-to-deportation pipeline that will be accelerated by SB 4,” Libal said. “They can start by enacting policies that end discretionary arrests while ensuring that scarce public resources are not wasted on unnecessary immigration enforcement actions that terrorize the immigrant community.”
Problem Solvers with Jason Feifer Opinions expressed by Entrepreneur contributors are their own. 3 min read If you own an Apple mobile device, you have no excuse for not backing it up, because Apple gives you two very simple and free ways for duplicating and storing a copy of your information: iCloud and iTunes.The benefit of backing up using iCloud is that it’s largely automated and can happen wirelessly. The downside is Apple only gives you 5GB space for free, so if you need more, you have to pay for it.With iTunes, you don’t face quite the same space limitations. It creates backups of your iPhone, iPad or iPod touch right on your computer. Therefore, the amount of space allotted to your backups is fully in your control. It’s a slice of the free space on your PC or Mac. If you back up using iTunes, you can do it by connecting your iO device to your computer or by turning on wireless syncing with iTunes over Wi-Fi. Let’s see how it’s done.How to back up iPhone or iPad using iTunesBefore you make a backup of your iPhone or iPad using iTunes, it’s a good idea to check whether you have the latest latest version of iTunes (go to Help > Check for Updates), but it’s often not necessary.Wireless syncMake sure iCloud is turned off. On your iPhone, go to Settings > [Your Name] > iCloud > iCloud Backup and toggle iCloud Backup to off. Then go to Settings > General > iTunes Wi-Fi Sync, which will prompt you to connect your iPhone to your PC. Sign in to iTunes using your Apple ID and look for the small iPhone icon.In the menu that appears on the left, select Summary and scroll down to Options. Select “Sync with this iPhone over Wi-Fi” and click Apply on the bottom right.Disconnect your iPhone from the PC; if your PC and iPhone are on the same Wi-Fi network, your phone should appear in iTunes and allow for wireless backups.With a CableConnect your iPhone or iPad to your computer and launch iTunes. Your phone will appear as a small icon up top.Click that phone icon, and in the left-hand menu under Summary, click the items you want to back up. If it’s music, for example, click Music and check the box next to Sync Music. Choose whether you want to back up your entire library or select tracks and albums. Click Apply and do the same for movies, TV shows, and whatever else you want to sync. Hear from business owners and CEOs who went through a crippling business problem and came out the other side bigger and stronger. September 20, 2017 Listen Now
Update 4:00 pm ET: We’ve added a reference to the list of items affected by the delay, released after the USTR’s initial announcement along with a comment by the president and a comment from the CTA.The United States Trade Representative (USTR) announced today that it will delay tariffs on certain products imported from China, including cell phones, laptops, and video game consoles, until December 15.On August 1, President Trump announced a 10% tariff on the remaining $300 billion worth of Chinese imports—notably centerpiece technology—excluded from the original trade talks. He said the new tariff would go into effect on September 1. During the USTR’s public comment and hearing process on the proposed expansion, “it was determined that the tariff should be delayed.”RECOMMENDED VIDEOS FOR YOU…logoCreated with Sketch. Tech This Out – Warner Streaming Service, Galaxy Note Renders And Nintendo Switch Lite7.10.2019 Tech This Out – Warner Streaming Service, Galaxy Note Renders And Nintendo Switch LiteMore VideosVolume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9Next UpThe 2019 Kindle Oasis01:26OffAutomated Captions – en-USLive00:0002:1402:14 “Certain products are being removed from the tariff list based on health, safety, national security and other factors and will not face additional tariffs of 10 percent,” the USTR said.You can read the entire list of items included in the December 15 tariff delay here.You’ll notice smartwatches, wearable fitness trackers, and Bluetooth audio devices are not on the December 15 delay list. Tariffs on those items will go into effect on September 1, as scheduled.“Next month, we’ll begin to pay more for some of our favorite tech devices,” said Gary Shapiro, president and CEO of the Consumer Technology Association (CTA). The December 15 delay allows some devices to reach the U.S. without tariffs in time for the holiday season, which was a prominent point of concern for game console manufacturers. According to a joint letter filed by Sony, Nintendo, and Microsoft in June, a tariff-caused rise in cost would have “likely put a new video game console out of reach for many American families,” during the 2019 holidays. Speaking to reporters, the president confirmed that the holiday shopping season influenced the decision to delay the tariffs. “We’ve delayed it so it won’t be relevant to the Christmas shopping season,” Trump said. Previously, the president insisted that China is paying the cost of his tariffs, not U.S. consumers — a claim most economists dispute.“Tariffs are taxes. The Chinese government doesn’t pay for them – Americans bear the burden,” Shapiro said.The delay incited an instant sign of relief for manufacturers and retailers. Following the announcement, Apple shares (which had plummeted after Trump’s August 1 tweets) rose 5% higher and Best Buy’s increased more than 8%. In the press release the USTR said it will specify which items are affected by the delay. We will update this story as it develops. iPhone 11: Release Date, Specs, Price and LeaksUS Senator Says Wireless Carriers Helping Trump Build ‘Surveillance State”iPhone 11 Pro’ May Be Apple’s Ultimate Smartphone
[embedded content]The work is still preliminary, years away from widespread clinical or commercial use. The data set isn’t big enough to train a reliable model, for one thing. But the challenges run even deeper. “Right now this technique is limited to cases where we have direct access to the cortex. If we wanted to do this for the mass market, of course, opening the skull is not an option,” says Tanja Schultz, a computer scientist at the University of Bremen and an early innovator in the field (and Herff’s PhD advisor). Also, Schultz says, “the electrode montage on different patients is usually based on their medical requirements, so the positioning of the electrodes is never the same across patients … The second problem is that brains are not the same. In general, the motor cortex layout is similar across subjects, but it’s not identical.” That makes it hard to generalize the models that turn those signals into speech.So for now, these good results are confined to people who have the ability to speak clearly but also happen to have their skulls cracked open. That’s not the planned use case, which might include people who’ve lost the ability to speak, or never had it. In them, no one knows if their motor cortices will still be able to send the signals that control the jaw, let’s say. “Whether or not the same algorithms will work in a population that cannot speak, that may only be able to be figured out in further steps in a clinical trial,” Chang said in a press briefing earlier this week. “There are some really interesting questions about how this will actually work in someone who’s actually paralyzed.”Chang’s team compared brain output from people actually saying words and then just miming the words, and got similar results. But they don’t know whether their method would work in other languages besides English (there’s no reason it wouldn’t; the available set of physical articulations should be the same for all humans)—or whether it works if people just think about speaking without actually speaking, or think of words without saying them. That’s all down the road. But for now, at least, it seems like someday you might be able to speak your mind without saying a single word.More Great WIRED StoriesLA’s plan to reboot its bus system—using cell phone dataWomen’s homicidal rage is all over TV—and it’s funnyVR’s true innovation isn’t technological—it’s humanEverything you need to know about cannabisA peek into the toolkit of the dangerous Triton hackers💻Upgrade your work game with our Gear team’s favorite laptops, keyboards, typing alternatives, and noise-canceling headphones📩 Want more? Sign up for our daily newsletter and never miss our latest and greatest stories Edward Chang keeps a cybernetic implant at his desk, which seems almost calculatedly cool. Chang is a lean, low-voiced neurosurgeon at UC San Francisco. The cybernetic implant—more properly a Brain-Computer Interface—is a floppy, translucent plastic square about the size of my hand, embedded with a 16-by-16 array of titanium dots, each about the size of a cupcake sprinkle. This part sits on top of a brain. Half a dozen wires, white as iPhone cables, run from the square and terminate in copper leads. This is the interface part, the part that plugs into a computer.Through some clever processing, Chang has used the output from these BCIs to do something remarkable. If a person has one in their head, while they talk, Chang’s team can take readings from their motor cortex—recording the activity corresponding to speech or, more specifically, the movement of the mouth, the tongue, and the jaw. Then some software can turn that brain activity into digitally synthesized, accurate, comprehensible speech—no human talking required.The square sits on top of your brain. The copper leads plug into a computer.UCSFChang clicks over to a picture on his computer. It’s a person in a hospital bed, head encased in bandages—with a cable snaking out from underneath. “This person is speaking into a microphone, and we’re recording that brain activity in real time,” he says. “Our job has been to understand how that electrical activity, that code of information that’s transmitted by electrical signals in the brain, actually gives rise to speech.” For going on a decade, researchers around the world have been working on this problem—trying to understand the brain’s native tongue, so to speak, and restore a voice to people with paralysis or illness, people who can imagine themselves speaking but can’t actually do it. And as a paper by Chang’s group in the journal Nature this week shows, they’re getting close. In a way, virtual mind reading is just a happy side effect. Chang’s specialty is treating seizures; the BCI is a kind of targeting system. If someone has intractable, frequent ones, Chang’s team opens up their skull and puts the array onto their brain to find the source of the seizures and, ideally, make a surgical fix. But that means waiting around, sometimes for days, for a seizure to strike. “A lot of our patients are really bored. Sometimes when it goes past a couple of days, when you’re just stuck in a bed, they kind of welcome the research team to come in and break it up,” Chang says. That means they might play along with experiments. Chang got five people to say yes.Brains don’t talk much, as a rule. But they’re not quiet, either—fizzing with message-carrying molecules among an uncountably complicated thicket of neurons. Still, despite the seeming ubiquity of functional magnetic resonance imagery in stories about “the part of the brain that controls X,” scientists don’t really know what’s going on in there. Functional MRI images actually blur spatially over relatively huge chunks of think-meat, and over several seconds of time. Very low resolution. Electroencephalograms take a faster snapshot, but of the entire brain at once. So neural interfaces like the ones Chang uses—deployed in the past to allow physically paralyzed people to control computers—offer an opportunity for more detailed “electrocorticography,” reading the activity of the brain more directly.But how to translate an inner monologue to out-loud speech? Chang’s group does it in two steps. First they use a machine-learning algorithm to sync up their recordings of the motor cortex as a person’s mouth moves with the acoustics of the words that movement produces. They use this to train a virtual mouth, essentially a simulation of mouth parts which they can then control with output from the BCI. Chang’s team recorded his five participants talking and electrocorticographically recorded their brains. Then he used those brain recordings to teach a computer to make sounds with a simulated mouth. The mouth produced speech, which listeners recruited on Amazon’s Mechanical Turk were mostly able to transcribe, roughly.“This is currently a superhot topic, and a lot of very good groups are working on it,” says Christian Herff, a computer scientist at Maastricht University. His team similarly recorded motor cortex activity, but in people with their brains opened up on an operating table, awake and talking while waiting for surgery to remove tumors. Herff’s team went directly from the recordings to a machine-learning trained audio output, bypassing the virtual mouth. But it worked pretty well too. Machine learning has gotten better, electrocorticography has improved, and computer scientists, linguists, and neurosurgeons are all collaborating on the science—leading to a minor boom in the field, Herff says.Other approaches are chasing the same goal of turning brain activity directly into speech. In a paper earlier this year, a team at Columbia University showed it could generate speech using recordings from the auditory cortex—the part that processes sound—instead of the motor cortex. Right now, people who can’t physically make speech often have to use letter-by-letter technologies to spell out words, a much slower process than actual talking. These researchers would like to give those people a better option. “What approach will ultimately prove better for decoding imagined speech remains to be seen, but it is likely that a hybrid of the two may be best,” says Nima Mesgarani, the Columbia engineer who led that team.
The fungus Candida albicans causes candidiasis, or thrush. (Credit: Kateryna Kon/Shutterstock)It seems like every few years there’s a virus or bacterium that threatens human health in a new way. But a new fungus that is a threat to humans? That doesn’t happen very often. That’s why we in the medical mycology community – the people who study dangerous fungi – are so intrigued and concerned by news reports about a new, deadly fungus called Candida auris.C. auris is believed to have been first identified in 2009 in the ear canal of a patient in Japan, but has taken the medical community by surprise with its rapid spread across the globe in the last decade. C. auris has now been detected in about 20 countries and shows no evidence of stopping.What makes this well-traveled fungus fascinating and scary? Unlike other species of Candida, it is known to survive in hospital rooms for prolonged periods of time and is responsible for several outbreaks due to patient-to-patient transmission. The most concerning characteristic of this fungus, however, is its ability to withstand anti-fungal treatment.We are a team of medical mycologists working at Tufts University and specializing in the study of a different fungus, Candida albicans, and how it affects human health. We have been interested in C. albicans for years because its interactions with humans are so complex: Sometimes it seems friendly and sometimes it is our enemy. The new fungus C. auris seems very mysterious but we believe we can use what we have learned from studying other fungi to deal with this new organism.A Formidable New AdversaryFungi are among the most successful, resilient and fascinating groups of organisms on Earth. In fact, the largest organism on Earth is believed to be a mushroom. We do not know exactly how long fungi have been around, but it is believed that they might be some of the oldest land dwellers on Earth.During their existence, fungi have dealt with a multitude of global catastrophes, including five – and perhaps a coming sixth – mass extinctions. In order to survive and thrive during these extreme conditions, fungi have developed amazing strategies which have allowed them to conquer every environment imaginable. Out of the estimated 1.5 to 5 million fungal species on Earth, about 300 are able to cause disease in humans. In the case of C. auris, we know whom it is related to, but we do not know where it came from or how people acquire it.Fungi are important in the natural environment as well as food and drug production. (Credit: Rattiya Thongdumhyu/Shutterstock)Unlike anti-bacterials, the number of types of useful anti-fungal drugs is quite limited. There are only three main classes, and the chance of discovering new drugs is limited by the fact that fungi are in the group of organisms called eukaryotes, as humans are, which makes it difficult to find a drug that can kill a fungus but not a person. Additionally, anti-fungal resistance has been emerging over the past few decades in some fungi that cause disease in humans, but C. auris’ resistance to anti-fungals leaves other resistant fungi in the dust. Some C. auris strains are resistant to all classes of clinically used anti-fungals, which is extremely alarming.C. auris is also able to form biofilms, which are microbial communities attached to a surface and protected by a “glue-like” layer. The architecture of the biofilm protects C. auris from anti-fungals and immune system attacks. In the context of health care, microbial biofilms often form on plastics such as catheters, pacemakers and other implanted devices. These biofilms have been well studied for many microbes, but we do not fully understand the importance of biofilms formed by C. auris in the context of human disease.Where did this new pathogen come from? Why is it highly drug-resistant and able to spread so easily? How does it interact with our body and the other microbes in and on our body? While we don’t know much about C. auris yet, we know quite a bit more about its distant cousin, C. albicans.Lessons From C. albicansThe fungus C. albicans was first described by Hippocrates in 400 B.C. when he was describing oral thrush, a disease characterized by white lesions that form in the oral cavity when there is overgrowth of C. albicans. Since then, C. albicans has become one of the most studied fungi next to Saccharomyces cerevisiae, the baker’s and brewer’s yeast.C. albicans can cause fatal infections in humans, but more commonly this fungus resides in the human body, in the gut or on the skin, as a harmless member of the microbiome, which is the whole collection of microorganisms in and on our bodies.In a study from the 1970s, investigators showed that if you test one-month-old babies for fungi, you find that almost every one of them had acquired a fungus, usually C. albicans. The conclusion was that it is completely normal for a person to have C. albicans in their body.Yet, if the person develops a weakened immune system, the C. albicans that was already inhabiting their gut could become dangerous by changing its shape to elongated cells known as hyphae. These hyphae are then able to invade and destroy tissue, enter the bloodstream and cause a potentially fatal infection.Fighting Fungi With FungiA few years ago, our group started to wonder why this happens. Why is it OK that humans would have a fungus in our bodies that might kill us if conditions changed? Is there anything that the fungus does that might be good? We decided to investigate this question using a mouse model of infection.We found that mice that carried C. albicans in their guts were protected from lethal doses of the bacterium Clostridioides difficile (C. diff). These findings showed that C. albicans has wide-ranging effects on its human host and in some situations could actually be beneficial.Many aspects of C. albicans biology have been studied. We have a good understanding of what type of conditions push C. albicans to become a disease-causing organism and form biofilms. We also have identified some of the tricks that allow it to become drug resistant, such as acquiring mutations in a gene called ERG11. Interestingly, the ERG11 gene of C. auris has also acquired mutations that contribute to its drug resistance.So why is it important to consider C. albicans and other related Candida species when we are dealing with C. auris? If we understand some of the complex ways that C. albicans interacts with humans, this knowledge gives us a window to understand how C. auris might cause disease in people. Additionally, the lessons learned from studying C. albicans and other related fungi could help us develop solutions to deal with C. auris.Know thy enemy, in this case, by understanding its family.This is a guest post from Carol A Kumamoto, Professor of Molecular Biology and Microbiology, Tufts University and Jesus A. Romo, Postdoctoral Fellow in Molecular Biology and Microbiology, Tufts University. This article reflects the views of the authors.This article is republished from The Conversation under a Creative Commons license. Read the original article.
Technology | Archive Cloud Storage | November 19, 2018 Intelerad Launches Nuage Disaster Recovery Platform November 19, 2018 — Intelerad Medical Systems announced the launch of the nuage Disaster Recovery (DR) Platform. read more News | Archive Cloud Storage | December 20, 2018 IMS Announces Integration of Cloud Image Viewing Platform With Google Cloud International Medical Solutions (IMS) recently announced it will provide Google Cloud account users with the ability to… read more Carestream Health has signed an agreement to sell its healthcare information systems (HCIS) business to Philips Healthcare. This includes its radiology and cardiology PACS and reporting software. Image by geralt on Pixabay News | Remote Viewing Systems | July 16, 2019 Anatomage Releases Anatomage Cloud Platform Anatomage Inc. released an update to the Anatomage Cloud platform that allows medical and dental professionals to… read more News | Enterprise Imaging | June 27, 2019 Ambra Health Announces Integration With Box Ambra Health announced an integration with Box to enable the sharing of medical imaging directly from within Box’s… read more News | Radiology Business | March 07, 2019 Carestream Health To Sell its Healthcare IT Business To Philips Carestream Health has signed an agr read more News | Vendor Neutral Archive (VNA) | February 07, 2019 Connecticut, California Imaging Centers Deploy Ambra Cloud VNA Ambra Health announced that Naugatuck Valley Radiology and Insight Imaging are among the latest groups of leading… read more News | Remote Viewing Systems | July 30, 2018 Children’s Hospital Colorado to Manage Medical Images Via the Cloud With Nucleus.io Platform NucleusHealth and Children’s Hospital Colorado’s (Children’s Colorado) Center for Innovation have formed a strategic… read more At RSNA 2009, Accelarad expands its new SeeMyRadiology.com platform to provide universal access to medical images across the entire healthcare continuum through a single comprehensive Web portal for hospitals, radiologists, physicians and patients. A software-as-a-service solution (SaaS), SeeMyRadiology.com utilizes innovative cloud computing architecture to store all client images on a centralized cluster of servers. Authorized users upload and access appropriate files, independent of location and native imaging application, to manage and share data virtually, participating in a true SaaS experience. SeeMyRadiology.com eliminates the problems of LAN-based PACS storage silos and CD/DVD duplication, enabling unrelated authorized medical departments, enterprises and communities to share electronic images easily. The platform safeguards and speeds data sharing with sophisticated built-in permissions, encryption and compression for image routing, (we repeat this word a lot and I think routing implies sharing), viewing, and archiving without costly IT maintenance. Workflow tools are incorporated for those who need to view, interpret or report on studies. FacebookTwitterLinkedInPrint分享 News | Vendor Neutral Archive (VNA) | September 04, 2018 Novarad Highest Rated in Customer Satisfaction on Gartner Peer Insights VNA Category Novarad Healthcare Enterprise Imaging has taken the highest rated spot on Gartner’s Peer Insights technology review… read more Technology | September 21, 2009 Accelarad Expands SeeMyRadiology.Com at RSNA 2009 News | Enterprise Imaging | August 31, 2018 Greenville Health System Adopts Agfa HealthCare Enterprise Imaging System Agfa HealthCare and Greenville Health System (GHS), South Carolina, announced the successful implementation of a… read more News | Enterprise Imaging | August 09, 2018 Visage Signs Mercy for Visage 7 Open Archive Visage Imaging Inc. announced that it has signed a seven-year contract with Mercy, the fifth largest Catholic health… read more Related Content
Toshiba will showcase Spot Fluoro, a dose management tool for Infinix-i vascular X-ray systems. Spot Fluoro allows clinicians to view a region of anatomy using live fluoroscopy while viewing the Last Image Hold surrounding area, resulting in lower dose and a larger image display area than offered by previous technology.Toshiba Showcases Infinix VF-i Bi-plane with Dual Mid-size Panel DetectorsImproving throughput and ease for clinicians during diagnostic, interventional and hybrid procedures, Toshiba America Medical Systems, Inc. will showcase the Infinix VF-i bi-plane with dual 12? x 12? mid-size flat panel detectors (FPDs). FPDs placed on flexible C-arms provide unprecedented patient access, allowing interventional radiologists to increase efficiency and perform complicated procedures more quickly. Additionally, Variable Dose Mode, Virtual Collimation, Digital Zoom Fluoro and extensive pulse fluoro frame rate selections place comprehensive dose management features tableside. When combined with Toshiba’s proprietary Next Generation AIP, the system provides enhanced visualization of small vessels and intricate devices.For more information: www.medical.toshiba.com FacebookTwitterLinkedInPrint分享 News | Computed Tomography (CT) | March 04, 2019 Aidoc Announces CE Mark for AI-based Pulmonary Embolism Workflow Tool Artificial intelligence (AI) radiology solution provider Aidoc announced the commercial release of its CE-marked… read more Related Content Technology | Radiation Dose Management | April 04, 2019 Omega Medical Imaging Launches AI-enabled FluoroShield for Radiation Reduction The U.S. Food and Drug Administration (FDA) granted Omega Medical Imaging 510(k) clearance to offer their artificial… read more Technology | Interventional Radiology | June 24, 2019 Mentice and Siemens Healthineers Integrate VIST Virtual Patient With Artis Icono Angiography System Siemens Healthineers and Mentice AB announced the collaboration to fully integrate Mentice’s VIST Virtual Patient into… read more 360 Photos | Angiography | May 17, 2019 360 View Inside a Cath/EP Lab at Baylor Heart Hospital This is a view inside one of the 11 cath labs at … read more Technology | Radiation Dose Management | May 23, 2019 ControlRad Announces FDA Clearance and Launch of ControlRad Trace ControlRad Inc. announced that the U.S. Food and Drug Administration (FDA) granted 510(k) clearance for its ControlRad… read more News | CT Angiography (CTA) | July 11, 2019 Mednax National Cardiac Centers of Excellence Program Highlighted at SCCT 2019 Mednax Inc. and Mednax Radiology Solutions announced that Chief Medical Officer Ricardo C. Cury, M.D., FSCCT, will… read more Philips and Microsoft have partnered to develop an augmented reality system to help imporve workflow and procedural navigation in the cath lab. Physicians wearing visors can view and interact with true 3-D holograms above the patient on the table and manipulate the image with voice and hand motion commands to avoid breaking the sterile field. News | CT Angiography (CTA) | July 24, 2019 WVU Medicine Installs First Alphenix 4D CT in the U.S. The West Virginia University (WVU) Heart and Vascular Institute is the first hospital in the country to acquire the… read more Technology | Angiography | March 01, 2019 iSchemaView Launches RAPID Angio iSchemaView announced the release of RAPID Angio, a complete neuroimaging solution for the angiography suite that… read more Technology | November 09, 2012 Toshiba Highlights Advances in Angiography Imaging Systems News | Advanced Visualization | February 25, 2019 Philips and Microsoft Showcase Augmented Reality for Image-Guided Minimally Invasive Therapies Philips will unveil a new mixed reality concept developed together with Microsoft that the company says is designed for… read more Technology | Mobile C-Arms | February 18, 2019 Philips Launches Zenition Mobile C-arm Platform Philips announced the launch of Philips Zenition, its new mobile C-arm imaging platform. Mobile C-arms are X-ray… read more
News | PACS | August 09, 2019 Lake Medical Imaging Selects Infinitt for Multi-site RIS/PACS Infinitt North America will be implementing Infinitt RIS (radiology information system)/PACS (picture archiving and… read more Related Content February 19, 2018 – DenseBreast-info.org (DB-I) announced plans for international expansion with specialized content for Europe and neighboring countries.The three-year-old non-profit, medically sourced website on fibroglandular breast density will provide a section featuring European screening guidelines by country and additional content developed and curated by a newly appointed coalition of physicians from Europe and neighboring countries. Breast cancer remains the most common cancer among European women, and about 40 percent of both American and European women have dense breasts. Dense fibroglandular breast tissue can mask cancer detection on mammography and increases risk of developing breast cancer.Internationally recognized breast cancer radiologist Athina Vourtsis, M.D., Ph.D., director and founder of Diagnostic Mammography Center in Athens, Greece, will serve as the organization’s European liaison. Cheryl Cruwys, a career educator with administration experience in Europe who has been instrumental in breast density education in the United Kingdom, joins DB-I as European education coordinator.Both will play a key role in European content development, along with coalition members who include:Prof. László Tabár of Sweden;Prof. Alexander Mundinger and Prof. Christiane Kuhl of Germany;Prof. Michael Fuchsjäger of Austria;Prof. Enzo Durante and Dr. Adriana Bonifacino of Italy;Prof. Boris Brkljačić of Croatia;Prof. Dragana Djilas of Serbia;Dr. Chrysa Tziakouri-Shiakalli of Cyprus;Dr. Nick Perry of the U.K.; andProf. Isabelle Tomassin-Naggara of France.Website content will be generated by their collective expertise and will offer a well-rounded perspective on the screening and risk considerations of dense breast tissue to advance a better educated dialogue on the topic.Commenting on DB-I’s growth, Wendie Berg, M.D., Ph.D., the organization’s chief scientific advisor, noted, “The website is rich in medically sourced information. The European coalition will have its own board representing Europe and nearby nations. We are thrilled to expand this website to the European clinical community and help educate on this very important issue.”The organization is currently in the process of securing unrestricted educational grants to support the expansion planned for October 2018. Donors interested in supporting this initiative should contact the organization for more information at firstname.lastname@example.org (link sends e-mail).For more information: www.densebreast-info.orgRelated Breast Density ContentVIDEO: The Impact of Breast Density Technology and LegislationVIDEO: What is New in Breast Imaging TechnologyBreast Density Reporting Advances on National and State Levels FacebookTwitterLinkedInPrint分享 News | Breast Density | February 19, 2018 DenseBreast-info.org Launches European-Focused Education Coalition Website will have new section featuring European screening guidelines by country, other content assembled by team of physicians from Europe and neighboring countries Technology | Mammography Reporting Software | July 25, 2019 Hologic Partners With MagView to Develop Unifi EQUIP Solution Hologic announced a partnership with mammography information solutions provider MagView to develop Unifi EQUIP, an… read more News | Artificial Intelligence | August 13, 2019 Artificial Intelligence Could Yield More Accurate Breast Cancer Diagnoses University of California Los Angeles (UCLA) researchers have developed an artificial intelligence (AI) system that… read more read more Qlarity Imaging’s software is used to assist radiologists in the assessment and characterization of breast lesions. Imaging features are synthesized by an artificial intelligence algorithm into a single value, the QI score, which is analyzed relative to a database of reference abnormalities with known ground truth. Image courtesy of Business Wire. News | Mammography | August 14, 2019 Imago Systems Announces Collaboration With Mayo Clinic for Breast Imaging Image visualization company Imago Systems announced it has signed a know-how license with Mayo Clinic. The multi-year… read more Image courtesy of Imago Systems Technology | Artificial Intelligence | July 18, 2019 Paragon Biosciences Launches Qlarity Imaging to Advance FDA-cleared AI Breast Cancer Diagnosis System Paragon Biosciences LLC announced the launch of its seventh portfolio company, Qlarity Imaging LLC, which was founded… read more IBM collected a dataset of 52,936 images from 13,234 women who underwent at least one mammogram between 2013 and 2017, and who had health records for at least one year prior to the mammogram. The algorithm was trained on 9,611 mammograms. Image courtesy of Radiology. Feature | Artificial Intelligence | July 19, 2019 | Michal Chorev AI Models Predict Breast Cancer With Radiologist-level Accuracy Breast cancer is the global leading cause of cancer-related deaths in women, and the most commonly diagnosed cancer… read more News | Mammography Reporting Software | July 26, 2019 Ikonopedia Releases Automated Combined Reporting Package at AHRA Ikonopedia showcased its recently released Automated Combined Reporting package and its entire suite of structured… read more News | Breast Imaging | August 02, 2019 Volpara to Distribute Screenpoint Medical’s Transpara AI Solution Volpara Solutions and ScreenPoint Medical BV signed an agreement under which Volpara will sell ScreenPoint’s Transpara… read more News | Ultrasound Women’s Health | July 11, 2019 FDA Clears Koios DS Breast 2.0 AI-based Software Koios Medical announced its second 510(k) clearance from the U.S. Food and Drug Administration (FDA). Technology | Breast Biopsy Systems | July 24, 2019 Fujifilm Releases Tomosynthesis Biopsy Option for Aspire Cristalle Mammography System Fujifilm Medical Systems U.S.A. Inc. recently expanded its breast imaging solutions with the launch of its… read more
Group 2 is likely to be load-shed from 3pm to 6pm, followed by Group 3 from 6pm to 9pm.To know your group when load-shedding strikes, click HERE WebsiteWebsiteWebsite WebsiteWebsiteWebsite WebsiteWebsiteWebsite
The Ladysmith Association for the Aged (Lafta) held a dinner and dance last night (Saturday) at the Civic Hall.Young and old alike turned up in numbers to enjoy the night.The tables were beautifully laid out for the guests to enjoy a delicious meal and drinks. The band ‘Men in Black’ was there to entertain the crowd with golden oldies as well as the latest, popular songs.Lucky draws also formed part of the evening’s entertainment, with lovely prizes to be won.Guest speakers took the stage, including Lafta president Mr Naidoo, who thanked everyone for their attendance.After the scrumptious dinner, the band revved up the tempo and everyone danced the night away.The aim of the event was to raise funds for the new Lafta premises. WebsiteWebsiteWebsite WebsiteWebsiteWebsite WebsiteWebsiteWebsite
The scene of this morning’s truck accident that blocked traffic on the N3 at Van Reenen has been cleared.Traffic is moving as normal after a contraflow system was in place for a short period of time.No one was injured in the accident. WebsiteWebsiteWebsite WebsiteWebsiteWebsite WebsiteWebsiteWebsite
Air Tahiti Nui expanded its codeshare partnership with Japan Airlines (JAL) over winter 2018/19 with the carrier to codeshare on the following JAL operated services, effective 28-Oct-2018 (Routes Online, 29-Oct-2018):Tokyo Haneda-Fukuoka;Tokyo Haneda-Sapporo New Chitose;Tokyo Narita-Hong Kong;Tokyo Narita-Nagoya;Tokyo Narita-Osaka Itami.The post Air Tahiti Nui expands codeshare with Japan Airlines appeared first on Discover the South Pacific.Source: Blog
May 4, 2004 Around 50.000 people visit the Arcosanti Visitors Center each year. The gallery offers a beautiful collection of ceramic and bronze bells and tiles, publications, T-shirts and postcards. Tours start at 10 am to 4 pm and are available every hour on the hour. For large tour groups please call for reservation.[Photo & Text: sa] Palma Burdick and manager Nina Howard are part of the cheerful gallery staff.[Photo & Text: sa] Archive volunteer Siobhan Watts interprets the tour information into sign language for hearing impaired visitors. Tour guide Josh Krimmel.[Photo & Text: sa] Myriam Barrancos-Ram is one of a few multi-language tour guides. The Arcosanti staff and students have come from many different countries. Languages, besides English, spoken at Arcosanti at this time are Japanese, French, Spanish, Italian, German, Tamil and a little Chinese.[Photo & Text: sa]
Several women who have accused Bill Cosby of sexual assault are outraged that a new national museum celebrating black history will recognize the actors work without mentioning the dozens of allegations against him”If they just speak about the contributions, I’d say I am sorry, 75, “With the passing of Nancy Reagan, Swift vs. suppliers to buyers.
Nigerians have reacted to President Muhammadu Buhari’s memo to the National Assembly to vire N228, I am prepared to provide the necessary information to America or to Europe or to the country which can buy me out of Thai prison. looks like an arrowhead. “BJP has come to symbolise the economic and political right. Why are they so worried about whether or not I met Rahul? one of the strongest signs yet a full U.The surprise White House statement drew qualified support from the leading Senate Democrat.Report reaching DAILY POST has it that the officers of the Nigeria Police on Thursday stormed the national office of the Peace Corps of Nigeria located at JabiA colleague of the doctor told the newspaper that Dr Zhao started work at 6pm on 28 December and finished seeing outpatients at around midnight before checking the hospital wards.’’ NAN recalled that early this year, and Esquire Network.